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Clinical Trials
PipelineClinical Trials
A single and repeated dose escalation study to evaluate the safety, pharmacokinetics and preliminary pharmacodynamics of RBD1016 in subjects with chronic hepatitis B virus (HBV) infection

“A randomized, double-blind, placebo-controlled, single and repeated dose escalation, phase I clinical study to evaluate the safety, pharmacokinetics and preliminary pharmacodynamics of RBD1016 in subjects with chronic hepatitis B virus (HBV) infection" is ongoing.

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A clinical trial to evaluate the safety and pharmacokinetics of RBD1016 in healthy subjects

"A randomized, double-blind, placebo-controlled, single-dose escalation phase I clinical trial to evaluate the safety and pharmacokinetics of RBD1016 in healthy subjects" is ongoing

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A phase IIa clinical trial to evaluate the safety, efficacy, and pharmacokinetics of ISIS 560131 in patients of Metastatic Castration-Resistant Prostate Cancer with Positive androgen receptor splicing variant 7 (AR-V7)

"A phase IIa clinical trial to evaluate the safety, efficacy, and pharmacokinetics of ISIS 560131 in patients of Metastatic Castration-Resistant Prostate Cancer with Positive androgen receptor splicing variant 7 (AR-V7) " is on-going.

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Clinical study on type 2 diabetes mellitus with poorly controlled blood glucose upon diet and exercise interventions

"A multi-center, randomized, double-blind, placebo-controlled，2:1 parallel-group phase II clinical study to evaluate efficacy and safety of ISIS 449884 injection monotherapy in patients with type 2 diabetes mellitus with poorly controlled blood glucose following diet and exercise interventions" is ongoing.

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Clinical study on type 2 diabetes mellitus with poorly controlled blood glucose following Metformin monotherapy

" A multi-center, randomized, double blind, placebo-controlled, 2:1 parallel-group phase II clinical study to evaluate efficacy and safety of ISIS 449884 Injection combined with metformin in patients with type 2 diabetes mellitus with poorly controlled blood glucose following Metformin monotherapy" is ongoing.

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